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Even today the weather forecast by a local fisherman is n times more accurate than what modern technology predicts!
The local fisherman looks at the system as a whole, technology tries to unsuccessfully break into parts. Removing, modifying or introducing new genes has an impact (positive or negative but rarely neutral) on the entire system, and introducing such genetically modified strains into production without studying the complete nature of the change is an invitation for disaster.
The growing space occupied by Facebook and Google continued to be a neverending ping pong battle in 2017, with Google eventually clinching the year by bringing more traffic to publishers than Facebook.
Genetic engineers similarly were used to searching inside the DNA to find genes with specific functionality and simply copy paste them in other species without really understanding the overall impact of these INDUCED genetic changes.